A further 11 LRIP aircraft (nine MV-22 and two CV-22) were ordered in May 2003, 11 (eight MV-22 and three CV-22) in February 2004 and 11 (nine MV-22 and two CV-22) in January 2005.
The V-22 was approved for full-rate production in September 2005. The MV-22 achieved initial operating capability in June 2007 and left for its first operational deployment in Iraq in September 2007, with USMC Squadron 263. Initial operating capability for the CV-22 was achieved in March 2009, but a CV-22 flew a first search and recovery mission from Kirtland AFB, New Mexico, in October 2007. A five-year contract for 141 MV-22 and 26 CV-22 was placed in March 2008. 360 MV-22 (to replace CH-46 Sea Knight) and 50 CV-22 (to replace MH-53J Pave Low helicopters) are required.
The 100th V-22 Osprey was delivered in March 2008.
In July 2006, two MV-22 Ospreys completed flights crossing the Atlantic to take part in the flying display at Farnborough International Airshow. The MV-22 was deployed for the first time in an offensive combat mission known as Operation Cobra's Anger in December 2009.
The first five MV-22 Osprey containerised flight training devices (CFTD) were delivered to the USMC in 2009 to train aviation cadets on basic aircraft familiarisation and handling. The last CFTD was delivered in September 2010.
The V-22 achieved 100,000 flight hours milestone in March 2011.
In June 2011, the Israel Air Force (IAF) unveiled the decision to send its team to the US for evaluating the V-22 Osprey. Upon clear examination, the IAF will acquire V-22s to carry out search and rescue, and special covert operations. The Osprey will replace IAF's aging fleet of Sikorsky CH-53 Sea Stallion transport helicopters.